Safety pharmacology and subchronic toxicity of jinqing granules in rats
نویسندگان
چکیده
منابع مشابه
Safety pharmacology and subchronic toxicity of jinqing granules in rats
BACKGROUND Jinqing granules which are made of a mixture extract that contains Radix Tinosporae and Canarii fructus in proportions according to a longstanding formula have a good effect on the prevention and treatment of gastric ulcer disease. It has not been through safety through systematic toxicological studies, however. To provide basis for clinical application, we performed safety pharmacol...
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BACKGROUND "Jiedu Huayu" (JDHY) granules are traditional Chinese herbal compounds that have been used to treat severe liver injury for many years. The purpose of the current study is to evaluate the safety of JDHY granules. METHODS Subchronic toxicity was tested in male and female rats that were orally administered three different doses (80, 100, and 130 g/kg/d) of JDHY for 13 weeks. Clinical...
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Objective(s) Ocimum basilicum L. is widely used in folk medicine of many countries including Iran. Both O. basilicum and its oil extract have received considerable attention for their potential medicinal properties, but there are a few reports about possible toxicity of this plant. Therefore, in the present study, acute and subchronic toxicity of O. basilicum hydroalcohlic extract have been ev...
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Essential oil has performed a variety of indirect services used as insect/pest repellent. The present study investigated the acute and subchronic toxicity of eucalyptus oil emulsion in water (EOE). In addition, we conduct safety pharmacology evaluation of EOE to supplement the toxicity tests and provide a basis for a comprehensive understanding of the toxicity of EOE. Acute administration of EO...
متن کاملsafety assessment of ocimum basilicum hydroalcoholic extract in wistar rats: acute and subchronic toxicity studies
objective(s) ocimum basilicum l. is widely used in folk medicine of many countries including iran. both o. basilicum and its oil extract have received considerable attention for their potential medicinal properties, but there are a few reports about possible toxicity of this plant. therefore, in the present study, acute and subchronic toxicity of o. basilicum hydroalcohlic extract have been eva...
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ژورنال
عنوان ژورنال: BMC Veterinary Research
سال: 2017
ISSN: 1746-6148
DOI: 10.1186/s12917-017-1095-3